For intracranial volumes, the intraclass correlation coefficient (ICC) was calculated to convey association within and between observers. In addition, we compared the predicted mean TBV values derived by our formula with the expected mean TBV predicted by the previously reported Jarvis' formula at each time point. The formulas to calculate intracranial structures volume derived from our data were created using a regression model. A t-test was used to compare the mean TBV and ICV values to previously reported values at each gestational week. A linear regression analysis was used to determine the gestational weekly age-related change adjusted for sex. The mean, SD, minimum, maximum, median, and 25th and 75th quartiles for intracranial structures volume were calculated per gestational week.

Three dimensional (3-D) volumetric parameters from slice-to-volume reconstructed (SVR) images, such as total brain volume (TBV), cortical gray matter volume (GMV), subcortical brain tissue volume (SBV), intracranial cavity volume (ICV), lateral ventricles volume (VV), cerebellum volume (CBV), brainstem volume (BM), and extra-cerebrospinal fluid volume (e-CSFV), were quantified by manual segmentation from two experts. The purpose of this study is to establish a reference of intracranial structure volumes in normal fetuses ranging from 19 to 37 weeks' gestation (mean 27 weeks).Ī retrospective analysis of 188 MRI examinations (1.5 T) of fetuses with a normal brain appearance (19-37 gestational weeks) from January 2018 to December 2021 was included in this study.

Clearview value metric mri